The name tretinoin comes from trans- retinoic , 24 and the name isotretinoin is the same root plus the prefix iso-.

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increased levels of triglycerides, serum creatinine and or hepatic enzymes are observed but do not usually necessitate interruption or withdrawal of tretinoin therapy.

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tetracyclines concomitant treatment with accutane isotretinoin and tetracyclines should be avoided because accutane isotretinoin use has been associated with a number of cases of pseudotumor cerebri benign intracranial hypertension , some of which involved concomitant use of tetracyclines.

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since antibiotics from the tetracycline group can also increase cranial pressure, patients should not be treated with tretinoin and tetracyclines simultaneously.

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